The common cold
Identifieur interne : 002A01 ( Main/Exploration ); précédent : 002A00; suivant : 002A02The common cold
Auteurs : Terho Heikkinen [Finlande] ; Asko J RvinenSource :
- Lancet (London, England) [ 0140-6736 ] ; 2003.
Abstract
Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the several viruses that cause the disease, the role of rhinoviruses is most prominent. About a quarter of all colds are still without proven cause, and the recent discovery of human metapneumovirus suggests that other viruses could remain undiscovered. Research into the inflammatory mechanisms of the common cold has elucidated the complexity of the virus-host relation. Increasing evidence is also available for the central role of viruses in predisposing to complications. New antivirals for the treatment of colds are being developed, but optimum use of these agents would require rapid detection of the specific virus causing the infection. Although vaccines against many respiratory viruses could also become available, the ultimate prevention of the common cold seems to remain a distant aim.
Url:
DOI: 10.1016/S0140-6736(03)12162-9
PubMed: 12517470
PubMed Central: 7112468
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The common cold</title><author><name sortKey="Heikkinen, Terho" sort="Heikkinen, Terho" uniqKey="Heikkinen T" first="Terho" last="Heikkinen">Terho Heikkinen</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Paediatrics, Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Paediatrics, Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="J Rvinen, Asko" sort="J Rvinen, Asko" uniqKey="J Rvinen A" first="Asko" last="J Rvinen">Asko J Rvinen</name><affiliation><nlm:aff id="aff2">Department of Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Helsinki</nlm:aff><wicri:noCountry code="subfield">Helsinki</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">12517470</idno><idno type="pmc">7112468</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112468</idno><idno type="RBID">PMC:7112468</idno><idno type="doi">10.1016/S0140-6736(03)12162-9</idno><date when="2003">2003</date><idno type="wicri:Area/Pmc/Corpus">000962</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000962</idno><idno type="wicri:Area/Pmc/Curation">000962</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000962</idno><idno type="wicri:Area/Pmc/Checkpoint">000963</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000963</idno><idno type="wicri:Area/Ncbi/Merge">000060</idno><idno type="wicri:Area/Ncbi/Curation">000060</idno><idno type="wicri:Area/Ncbi/Checkpoint">000060</idno><idno type="wicri:doubleKey">0140-6736:2003:Heikkinen T:the:common:cold</idno><idno type="wicri:Area/Main/Merge">002A11</idno><idno type="wicri:Area/Main/Curation">002A01</idno><idno type="wicri:Area/Main/Exploration">002A01</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The common cold</title><author><name sortKey="Heikkinen, Terho" sort="Heikkinen, Terho" uniqKey="Heikkinen T" first="Terho" last="Heikkinen">Terho Heikkinen</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Paediatrics, Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Paediatrics, Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="J Rvinen, Asko" sort="J Rvinen, Asko" uniqKey="J Rvinen A" first="Asko" last="J Rvinen">Asko J Rvinen</name><affiliation><nlm:aff id="aff2">Department of Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Helsinki</nlm:aff><wicri:noCountry code="subfield">Helsinki</wicri:noCountry></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="ISSN">0140-6736</idno><idno type="eISSN">1474-547X</idno><imprint><date when="2003">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the several viruses that cause the disease, the role of rhinoviruses is most prominent. About a quarter of all colds are still without proven cause, and the recent discovery of human metapneumovirus suggests that other viruses could remain undiscovered. Research into the inflammatory mechanisms of the common cold has elucidated the complexity of the virus-host relation. Increasing evidence is also available for the central role of viruses in predisposing to complications. New antivirals for the treatment of colds are being developed, but optimum use of these agents would require rapid detection of the specific virus causing the infection. Although vaccines against many respiratory viruses could also become available, the ultimate prevention of the common cold seems to remain a distant aim.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Herbert, Ap" uniqKey="Herbert A">AP Herbert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gonzales, R" uniqKey="Gonzales R">R Gonzales</name></author><author><name sortKey="Malone, Dc" uniqKey="Malone D">DC Malone</name></author><author><name sortKey="Maselli, Jh" uniqKey="Maselli J">JH Maselli</name></author><author><name sortKey="Sande, Ma" uniqKey="Sande M">MA Sande</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adams, Pf" uniqKey="Adams P">PF Adams</name></author><author><name sortKey="Hendershot, Ge" uniqKey="Hendershot G">GE Hendershot</name></author><author><name sortKey="Marano, Ma" uniqKey="Marano M">MA 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Kaesmayr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Warshauer, Dm" uniqKey="Warshauer D">DM Warshauer</name></author><author><name sortKey="Dick, Ec" uniqKey="Dick E">EC Dick</name></author><author><name sortKey="Mandel, Ad" uniqKey="Mandel A">AD Mandel</name></author><author><name sortKey="Flynn, Tc" uniqKey="Flynn T">TC Flynn</name></author><author><name sortKey="Jerde, Rs" uniqKey="Jerde R">RS Jerde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takkouche, B" uniqKey="Takkouche B">B Takkouche</name></author><author><name sortKey="Regueira Mendez, C" uniqKey="Regueira Mendez C">C Regueira-Méndez</name></author><author><name sortKey="Garcia Closas, R" uniqKey="Garcia Closas R">R Garcia-Closas</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Finlande</li></country><region><li>Finlande occidentale</li></region><settlement><li>Turku</li></settlement></list><tree><noCountry><name sortKey="J Rvinen, Asko" sort="J Rvinen, Asko" uniqKey="J Rvinen A" first="Asko" last="J Rvinen">Asko J Rvinen</name></noCountry><country name="Finlande"><region name="Finlande occidentale"><name sortKey="Heikkinen, Terho" sort="Heikkinen, Terho" uniqKey="Heikkinen T" first="Terho" last="Heikkinen">Terho Heikkinen</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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